Expression of BCL-2 and KI-67 in Cyclical Endometrium and in Endometrial Hyperplasia
نویسندگان
چکیده
The Present study attempts to determine the relationship between proliferation and inhibition of apoptosis in normal endometrium hyperplasia, using monoclonal antibodies against marker, Ki-67 anti-apoptotic protein, Bcl-2 expression B-cell lymphoma 2 (Bcl – 2) Ki 67 cyclical proliferative secretory phase. includes Bcl endometrial hyperplasia.
منابع مشابه
ki-67, p53, Bcl-2 and Bax Expression in urothelial Carcinomas of urinary Bladder Mesanenin Ürotelyal karsinomlarında ki-67, p53, Bcl-2 ve Bax Ekspresyonu
Objective: The most important predictive parameter for the biological behavior of urothelial carcinomas except depth of invasion is the histological grade of the tumor. However, crucial discordances arise between pathologists because of subjectivity in histological grading schemes and these discordances cause difficulties especially in lowgrade tumors. The number of studies aiming to predict th...
متن کاملExpression Analysis of p53, Ki-67 and bcl-2 in Pre-Malignant Lesions of the Cervix
Objectives: The present study has tried to analyze the individual and combined expression of the three markers—p53, Ki-67 and bel-2-in HPV associated pre-malignant lesions of the cervix. Methods: Thirty-four cases of high-grade lesions, 21 low-grade cases and 18 normal cases were histologically assessed. HPV-DNA presence and the viral types were determined through PCR and RFLP, respectively. Ma...
متن کاملa comparative immunohistochemical study of ki-67 and bcl-2 expression in solid ameloblastoma and adenomatoid odontogenic tumor
background: solid ameloblastoma (sab) is an invasive tumor which infiltrates adjacent normal tissues. adenomatoid odontogenic tumor is a noninvasive tumor and never infiltrates surrounding normal tissues. the purpose of this study was to determine the biological behavior of these two epithelial odontogenic neoplasm by detecting ki-67 and bcl-2, which are mitotic and anti apoptotic markers respe...
متن کاملImmunohistochemical Expression of PCNA and Ki-67 in Periapical Granuloma and Radicular Cyst
Objectives: Periapical Granulomas (PGs) and Radicular Cysts (RCs), as the most common odontogenic lesions have yet unclear pathogenesis. This study was aimed to compare PCNA and Ki-67 expression in PGs and RCs and evaluate their possible relationship with two lesions. Methods: In this cross-sectional descriptive study, twenty PGs and twenty RCs were evaluated immunohistochemically using an a...
متن کاملMerkel cell carcinoma: mitoses, expression of Ki-67 and bcl-2 correlate with disease progression.
BACKGROUND There are conflicting data on markers of disease progression and outcome of Merkel cell carcinoma. OBJECTIVE We suggest to review histological and various immunohistochemical features of Merkel cell carcinoma specimens, in order to identify prognostic markers of clinical relevance. METHODS We collected paraffin-embedded blocks from primary tumours from 26 patients diagnosed with ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of pharmaceutical research international
سال: 2021
ISSN: ['2456-9119']
DOI: https://doi.org/10.9734/jpri/2021/v33i21a31363